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CHAPTER 7 - PERIPHERAL BLOOD
Histology Guide
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MICROGRAPH

NAME
EM 159 Platelet
TISSUE
Human Blood
IMAGE SIZE
8,268 x 9,368 pixels
295 MB
FILE SIZES
17,225 KB (grayscale)
17,290 KB (color)
MAGNIFICATION
1,600x
PIXEL SIZE
1.233 nm
SOURCE
Stanley L. Erlandsen
Department of Genetics, Cell Biology and Development
School of Medicine
University of Minnesota
Minneapolis, MN

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EM 159 Platelet

Platelet

Platelets (thrombocytes) are small non-nucleated cell fragments produced by budding from megakaryocytes under the influence of thrombopoietin. Platelets plug damaged blood vessel walls and are involved in the formation of blood clots.

are small biconcave discs (2 to 4 µm diameter).

  • (dark green) - covered by a thick glycocalyx.
    • - invaginations of the plasma membrane that facilitate signaling and secretion.
  • Hyalomere - outer region that contains circular rings of (cross-sections; purple) and microfilaments.
  • Granulomere - central region that contains organelles and secretion granules.
    • (red)
    • (cyan) - stores calcium (similar to sarcoplasmic reticulum in skeletal muscle).
    • (purple) - large granules that contain blood clotting substances.
    • (yellow) - smaller granules that contain factors that facilitate platelet adhesion and vasoconstriction.
    • λ Granules - similar to lysosomes (not visible).

Red blood cells (red) are visible around the platelet.

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