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CHAPTER 1 - THE CELL
Histology Guide
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MICROGRAPH

NAME
EM 304 Endoplasmic Reticulum
TISSUE
Liver
(hepatocyte)
IMAGE SIZE
6,858 x 4,820 pixels
35 MB
FILE SIZES
15,939 KB (grayscale)
20,203 KB (color)
MAGNIFICATION
Unknown
PIXEL SIZE
0.6628 nm
SOURCE
Don W. Fawcett
Department of Anatomy
Harvard Medical School
Boston, MA

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Robert L. Sorenson, Ph.D.

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University of Minnesota
Department of Genetics, Cell Biology and Development
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EM 304 Endoplasmic Reticulum

Endoplasmic Reticulum

Transmission electron micrograph (TEM) of a small region of the cytoplasm in a hepatocyte.

Endoplasmic reticulum (ER) forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae. The ER is the site of many cellular activities including the biosynthesis of proteins and lipids.

  • (RER, cyan) - cytosolic side covered by ribosomes that form peptides that enter the adjacent cisterna during synthesis.
    • Flattened cisternae
    • Abundant in cells that secrete proteins
  • (SER, yellow) - regions of ER that lack bound ribosomes
    • Network of tubular channels
    • Abundant in cells involved in steroid synthesis
  • Mitochondria (red)
  • Cytoplasm (green)
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