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CHAPTER 13 - ENDOCRINE GLANDS
Histology Guide
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MICROGRAPH

NAME
EM 321 Pancreatic Islet
TISSUE
Pancreas
IMAGE SIZE
10,062 x 7,029 pixels
202 MB
FILE SIZES
44.6 MB (grayscale)
63.8 MB (color)
MAGNIFICATION
Unknown
PIXEL SIZE
59.27 nm
SOURCE
Cyprian Weaver
Lillehei Heart Institute
School of Medicine
University of Minnesota
Minneapolis, MN

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Robert L. Sorenson, Ph.D.

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University of Minnesota
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EM 321 Pancreatic Islet

Pancreatic Islet

Pancreatic islets are highly vascularized and depends on blood supply to function efficiently. The intimate relationship between islet and acinar tissue is evident in vascular casts.

The simplest model is each has its own vascular network feed by arterioles, a glomerulus-like capillary net, and dedicated venous drainage. However, it is more integrated.

  • Blood supply to islets flows directly from arterioles and from acinar tissue.
  • Efferent capillaries carry blood to neighboring acini before joining the venous drainage.

This arrangement forms an insulo-acinar portal system that impacts nutrient sensing, paracrine communication, and the final hormonal output.

Several capillaries connect the islet with adjecent acini.

  • (yellow)
  • (green)
  • (cyan)

Many larger arteries (red) and veins (blue) are also visible.

Courtesy of Cyprian Weaver, Lillehei Heart Institute, School of Medicine, University of Minnesota, Minneapolis, MN

© 2005-2026. T. Clark Brelje and Robert L. Sorenson