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CHAPTER 19 - MALE REPRODUCTIVE SYSTEM
Histology Guide
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MICROGRAPH

NAME
EM 388 Spermatozoa
TISSUE
Uterus
IMAGE SIZE
11,798 x 9,038 pixels
320 MB
FILE SIZES
35,195 KB (grayscale)
39,702 (color)
MAGNIFICATION
Unknown
PIXEL SIZE
3.975 nm
SOURCE
David M. Phillips
The Population Council
Rockefeller University
New York, NY

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EM 388 Spermatozoa

Spermatozoa

Scanning electron microscopy (SEM) of spermatozoa on the endometrium of the uterus.

Sperm initially bind to the surface of endometrial epithelial cells. Specific receptors on both the sperm and the endometrial cells facilitate this binding.

  • Spermatozoa - head (orange) and tail (brown)
  • Endometrial Epithelial Cells (yellow)

Once sperm bind to the endometrium, they may undergo a process called capacitation, which prepares them for fertilization. Capacitation involves changes in the sperm membrane that allow them to penetrate the egg.

Endometrial cells play a crucial role in modulating the immune response to sperm. They can secrete factors that suppress inflammation and promote tolerance, preventing the immune system from attacking the sperm as a foreign invader.

Courtesy of David M. Phillips, The Population Council, Rockefeller University, New York, NY.

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